| DIRECTOR | PERIOD |
| Professor SAAP Karunanayke | 22-11-2021 to 21-11-2024 |
| Professor N Kamardeen (Acting) | 14-06-2021 to 31-10-2021 |
| Professor N Kamardeen | 14-06-2018 to 13-06-2021 |
| Professor N Kamardeen (Acting) | 01-02-2018 to 13-06-2018 |
| Dr IM Lakshman (Acting) | 01-11-2017 to 30-01-2018 |
| Mrs YMSK Weerakoon | 25-04-2016 to 31-10-2017 |
| Dr YMSK Weerakoon (Acting) | 23-02-2016 to 24-04-2016 |
| Dr DAC Silva | 17-10-2014 to 20-02-2016 |
| Rev. Professor W Wimalaratana (Acting) | 13-10-2014 to 16-10-2014 |
| Dr DAC Silva | 22-03-2014 to 12-10-2014 |
| Dr YMSK Weerakoon (Acting) | 05-03-2014 to 21-03-2014 |
| Dr DAC Silva | 01-02-2014 to 04-03-2014 |
| Dr YMSK Weerakoon (Acting) | 29-01-2014 to 31-01-2014 |
| Dr DAC Silva | 28-12-2013 to 28-01-2014 |
| Dr YMSK Weerakoon (Acting) | 20-12-2013 to 27-12-2013 |
| Dr DAC Silva | 26-02-2013 to 19-12-2013 |
| Ms MDM Abeyratne (Acting) | 22-11-2011 to 20-02-2013 |
| Dr SWP Mahanamahewa (Acting) | 17-10-2011 to 31-10-2011 |
| Dr YMSK Weerakoon (Acting) | 26-10-2010 to 16-10-2011 |
| Professor SA Nobert (Acting) | 04-10-2010 to 25-10-2010 |
| Dr YMSK Weerakoon (Acting) | 15-03-2010 to 03-10-2010 |
| Dr Pavithra Kailasapathy (Acting) | 30-12-2009 to 14-03-2010 |
| Professor SA Nobert (Acting) | 14-12-2009 to 29-12-2009 |
| Dr Pavithra Kailasapathy (Acting) | 16-11-2009 to 13-12-2009 |
| Professor MES Perera | 15-09-2008 to 14-11-2009 |
| Dr YMSK Weerakoon (Acting) | 18-02-2008 to 14-09-2008 |
| Professor SUK Ekanayake | 01-08-2007 to 14-02-2008 |
| Professor SUK Ekanayake | 02-08-2004 to 31-07-2007 |
| Professor Rohini Seneviratne | 01-07-2003 to 30-07-2004 |
| Professor SUK Ekanayake | 01-03-2001 to 30-06-2003 |
| Professor SUK Ekanayake (Acting) | 09-07-2000 to 28-02-2001 |
| Professor SUK Ekaratne | 09-07-1997 to 08-07-2000 |